Joseph Replogle on Twitter: "4. But Perturb-seq allows for more than clustering. scRNA-seq phenotypes allow us to study the phenotypic consequences of genetic perturbations, transcriptional programs, and “composite phenotypes” like RNA processing,
Direct capture of CRISPR guides enables scalable, multiplexed, and multi-omic Perturb-seq | bioRxiv
Perturb-seq – Enables Large-Scale Analysis of Complex Genetic Interactions Using CRISPR-Based Gene Perturbation and Single-Cell RNA Sequencing | RNA- Seq Blog
Approaches to maximize sgRNA-barcode coupling in Perturb-seq screens | bioRxiv
Targeted Perturb-seq enables genome-scale genetic screens in single cells | Nature Methods
Figure 4 from Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens | Semantic Scholar
Perturb-seq - Wikipedia
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response - ScienceDirect
Genome-Wide Perturb-Seq
A robust strategy combining CRISPR screening with RNA-sequencing... | Download Scientific Diagram
Researchers apply the Perturb-Seq method to a living organism for the first time | RNA-Seq Blog
In vivo Perturb-Seq | Xin Jin
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq - ScienceDirect
Massively parallel phenotyping of coding variants in cancer with Perturb-seq | Nature Biotechnology
Direct-capture Perturb-seq and pooled dual-guide cloning allows... | Download Scientific Diagram